The Liverpool vs Manchester United clash is set to be the blockbuster encounter for Matchday eight of the 2025/26 Premier League campaign as the two bitter English rivals fight for bragging rights in what should be a feisty clash at Anfield on Sunday, October 19.

The Liverpool vs Manchester United meetings have always been heated affairs, and it’s not expected to be any different this time around. Liverpool are reeling off a three-match losing streak, which includes having lost their last two Premier League games against Crystal Palace and Chelsea. They are eager to end their losing run and get back to winning ways at Anfield.

They are now facing a Manchester United side that are themselves extremely desperate to get a crucial away win. Something has got to give as the two more decorated Premier League teams of all time meet in the Liverpool vs Manchester United clash and entertain fans with an exciting display.

Match Details

Anfield
Liverpool, England
19 October
16:30 PM BST

Legendary English Rivalry Poised for Thrilling Clash Between Two Desperate Teams

The Liverpool vs Manchester United clash will be the first derby between the two English giants in the 2025/26 Premier League campaign, and a lot of stakes are riding on it for both teams.

Liverpool are desperate to get rid of their awful losing streak that is threatening to destroy their ambitions and push to retain the Premier League title at the end of the campaign.

Manchester United, meanwhile, need to defeat a major team like Liverpool for Ruben Amorim to prove that his side are able to hold their own against the very best.

The Liverpool vs Manchester United matches have recently significantly benefitted Liverpool, who are unbeaten in their last five Premier League games against Manchester United and won two of those games. However, Manchester United are unbeaten in their last two away games at Anfield, which they hope will work in their favor in the upcoming clash.

Liverpool have won all their home matches in the 2025/26 campaign and hope to keep that streak alive with a dominant performance against the Red Devils.

Can Mohamed Salah Rediscover His Mojo To Blow Away Manchester United?

Mohamed Salah has hit a bit of a rough patch for Liverpool in the early stages of the 2025/26 campaign, despite scoring the opening goal in the win over Bournemouth on the opening game.

The Egyptian forward, who scored 29 goals in the 2024/25 Premier League campaign, has failed to score in his last three matches, and pressure is mounting on him to come up with the goods for the Reds.

Fortunately, Salah is facing a team against whom he has a pretty great record against. Salah has scored 13 goals in 15 Premier League games against Manchester United and has scored in the last three meetings against them. He always seems to amp up his performance levels and become ruthless in front of goal against them, which is exactly what Salah will aim for to get back to scoring ways for Liverpool.

YOU MAY ALSO LIKE: Fantasy Football Matchweek 8: Buy, Sell, Injury Report

Is In-Form Benjamin Sesko Key for Manchester United’s Fight at Anfield?

Manchester United have had a pretty dreadful record when visiting Anfield over the last decade. The last time the Red Devils defeated Liverpool in their own yard was in the 2015/16 season, and they’ve either drawn or lost every away game against Liverpool ever since.

It’s obvious that Ruben Amorim’s side need something special to inspire them to get a win over Liverpool at their own yard.

They have to, of course, rely on a sturdy defensive showing from their players to frustrate the star-studded attacking force of Liverpool. But the Red Devils need to be clinical on the transitions to get a big win.

Benjamin Sesko has picked up his form in recent weeks and scored in his last two league games for the Red Devils. The Slovenian striker appears to be gaining momentum after joining from RB Leipzig, but he needs to perform in big games to prove his quality. What better opportunity to showcase yourself than at a Liverpool vs Manchester United game?

Sesko has to be clinical in driving Man United forward on the transitions and lethal with his finishing to surprise Liverpool and guide his side to a big result.

Liverpool vs Manchester United Injuries

Liverpool injuries: Alisson, Giovanni Leoni, Wataru Endo, Ibrahima Konate (doubt)

Manchester United injuries: Lisandro Martinez, Ayden Heaven, Noussair Mazraoui (doubt)

Liverpool vs Manchester United Predicted Lineups

Knowing the nature of this game, both Arne Slot and Ruben Amorim will be eager to field their strongest lineups in Liverpool vs Manchester United. Here we look at the Liverpool vs Manchester United predicted lineups.

Liverpool predicted XI: Giorgi Mamardashvili (GK), Jeremie Frimpong, Joe Gomez, Virgil van Dijk, Milos Kerkez, Ryan Gravenberch, Dominik Szoboszlai, Mo Salah, Florian Wirtz, Cody Gakpo, Alexander Isak

Manchester United predicted XI: Senne Lammens (GK), Lenny Yoro, Matthijs de Ligt, Luke Shaw, Diogo Dalot, Casemiro, Bruno Fernandes, Patrick Dorgu, Bryan Mbeumo, Mason Mount, Benjamin Sesko

Main Photo

Credit: IMAGO / Every Second Media

Recording Date: 04.10.2025